影片讲述了在一个虚构的时代，时局动乱，军阀割据的年代，百姓民不聊生，坊间谣传诡门十三针是一种神奇的针法，能够治疗各种疑难杂症，主人公赤瞳从小就是孤儿，父母就是被阴病所害，在与苏哮天结识之后，踏上了用诡门十三针治疗阴病的旅程，经历了一番艰难的斗争之后，苏哮天在与阴病的战斗中，不幸离世，赤瞳继承了苏哮天的意志，踏上了铲除阴病的路途……...

The seed bank in the Mars base was struck by meteor shower and Chinese astronauts went to rescue in duty bound. However, mysterious enormous fish appeared unexpectedly…...